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KMID : 1094020210380010036
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Journal of Veterinary Clinics
2021 Volume.38 No. 1 p.36 ~ p.40
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Canine Multicentric Large B Cell Lymphoma with Increased Mott Cells Diagnosed by Flow Cytometry
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Yang Ye-Seul
Jung Jae-Ha
Hwang Sung-Hyun
Kim Yong-Baek
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Abstract
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A 12-year-old dog was referred due to multiple superficial lymphadenopathy. On cytology, each lymph node showed different cell populations where some of them consisted of intermediate to large lymphocytes with frequent Mott cells. Presence of Mott cells along with immature lymphocytes made the cytological diagnosis challenging, and therefore, supplementary diagnostic tests including PCR for Antigen Receptor Rearrangement (PARR) assay and flow cytometry were performed. This case report illustrates the value of flow cytometry in the diagnosis of lymphadenopathy with ambiguous cytologic findings.
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KEYWORD
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flow cytometry, multicentric B cell lymphoma, Mott cells, immunophenotype, dog
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